Epidermal Growth Factor

Taxonomy

Code

mesh

Scope note(s)

  • A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.

Source note(s)

  • Medical Subject Headings

Display note(s)

Hierarchical terms

Epidermal Growth Factor

Equivalent terms

Epidermal Growth Factor

  • UF EGF
  • UF Epidermal Growth Factor-Urogastrone
  • UF Human Urinary Gastric Inhibitor
  • UF Urogastrone
  • UF beta-Urogastrone

Associated terms

Epidermal Growth Factor

3 Archival description results for Epidermal Growth Factor

3 results directly related Exclude narrower terms

Viktor Hamburger Oral History

  • FC132
  • Collection
  • June 30, 1983

Hamburger discusses major points in his long career as an embryologist – his early work in Germany with Hans Spemann and the study of the organizer effect; his experience coming to the United States in 1932 as a Rockefeller fellow and staying on after Hitler’s “cleansing of the professions” in Germany; joining the faculty of Washington University and his research there. Hamburger talks about his colleagues such as Rita Levi-Montalcini and their discovery of naturally occurring neuronal death, his work with Levi-Montalcini and Stanley Cohen on the discovery of nerve growth factor (NGF), and his study of animal behavior development and motility.

Hamburger, Viktor

Viktor Hamburger Oral History

  • OH067
  • Collection
  • 6/30/1983

Viktor Hamburger discusses major points in his long career as an embryologist – his early work in Germany with Hans Spemann and the study of the organizer effect; his experience coming to the United States in 1932 as a Rockefeller fellow and staying on after Hitler’s “cleansing of the professions” in Germany; joining the faculty of Washington University and his research there. Hamburger talks about his colleagues such as Rita Levi-Montalcini and their discovery of naturally occurring neuronal death, his work with Levi-Montalcini and Stanley Cohen on the discovery of nerve growth factor (NGF), and his study of animal behavior development and motility. Interviewed by Dale Purves, M.D. on June 30, 1983. OH067. Approximate Length 80 minutes.

Hamburger, Viktor