This collection consists of 724 photographs, drawings, diagrams, posters, newspaper clippings, and sheet music, and other ephemera related to the 21st General Hospital. The photographs primarily depict staff and patients of the 21st General Hospital from when it was stationed overseas 1942-1945, as well as views of hospital buildings and grounds. Drawings and diagrams include plans for wiring and plumbing, architectural and ground plans, and some schematic drawings of hospital equipment. Other ephemera in the collection include hand-drawn posters advertising Officers' Club dances, newspaper clippings from the St. Louis Post-Dispatch Pictures Section depicting operations at General Hospital 21, and cartoon watercolors depicting soldiers and Red Cross workers.