Collection VF05361 - Needleman, Philip, Vertical File


Reference code


Level of description



Needleman, Philip, Vertical File



0.02 Linear Feet

Name of creator

(Born 1939)

Biographical history

Philip Needleman is a professor emeritus of clinical pediartrics and former head of the department of pharmacology at Washington University School of Medicine, where he spent 25 years. After he left the university in 1989, Needleman became the senior vice president of Monsanto, president of Searle Research and Development in 1993, and senior executive vice president and chief scientist of Pharmacia from 2000 to 2003.

His research has brought about studies on the regulation of vascular, cardiac, and renal function, resulting in the discovery of the mechanism of organic nitrate tolerance, the first peptide angiotensin antagonists, and the atrial natriuretic factor (the hormone by which the heart communicates with the kidney). Needleman also conducted research on the role of prostaglandins in arthritis, where he contributed to the eventual discovery of Cox-2, the isoform of cyclooxygenase responsible for the inflammation and pain suffered by arthritis patients. His efforts in the science research industry at Monsanto and Searle led in the 1998 FDA approval of Celebrex. Needleman's career recognition includes the John Jacob Abel Award of the American Pharmacology Society and the Research Achievement Award of the American Heart Association. He returned to Washington University School of Medicine in 2004 as an associate dean and was subsequently named to the WUSM's board of trustees.

Scope and content

System of arrangement

Conditions governing access

The Vertical File Collection is open and accessible for research.

Technical access

Conditions governing reproduction

Users of the collection should read and abide by the Rights and Permissions guidelines at the Bernard Becker Medical Library Archives.

Users of the collection who wish to cite items from this collection, in whole or in part, in any form of publication must request, sign, and return a Statement of Use form to the Archives.

For detailed information regarding use of this collection, contact the Archives and Rare Book Department of the Becker Library (

Preferred Citation:

Item description, Reference Code, Bernard Becker Medical Library Archives, Washington University in St. Louis.

Languages of the material

  • English

Scripts of the material

  • Latin

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"Describing Archives: A Content Standard, Second Edition (DACS), 2013."

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Archivist's note

© Copyright 2019 Bernard Becker Medical Library Archives. All rights reserved.

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