Avioli, Louis V.

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Avioli, Louis V.

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1931-1999

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A graduate of Princeton and Yale Universities, Louis V. Avioli came to St. Louis in 1966, to lead the Division of Endocrinology at Jewish Hospital, a smaller teaching facility compared to its "sister" Barnes Hospital. Dr. Avioli's research focused on the causes of bone loss in postmenopausal women and the elderly, and in these early and pioneering years, he contributed to clarify the role of vitamin D in regulating calcium metabolism.

With his early trainees, Drs. Stanley Birge, Lewis Chase, John Haddad and Theodore Hahn, Dr. Avioli discovered the importance of key vitamin D metabolites in regulating intestinal calcium absorption and bone mineralization; recognized the negative effects of antiepileptics, in particular barbiturates, on vitamin D metabolism; and established the first radio-competitive methods to measure 25-hydroxy vitamin D in the blood, an assay that became the mainstay diagnostic test for vitamin D status. Source: https://bonehealth.wustl.edu/about-us/our-history/

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