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Most of the documents are course catalogs or commencement programs which are arranged in short series according to academic name. There are only a few unpublished items in the collection, including the notes of a Barnes medical student (1899-1900) and several Barnes Dental College contracts (1908-1915 with related letter).

This collection consists of 12 photographs and 1 diploma related to Barnes Medical College. The photographs primarily depict Gross Anatomy students and their dissected cadavers. Other depicted subjects include exterior views of Barnes Medical College, interior views of the Barnes Dental College Infirmary, group portraits of Barnes Medical College students, and a Doctor of Medicine diploma from Barnes Medical College awarded to Charles DeWitt Hibbetts.

This collection consists of 22 artifacts pertaining to the matriculation of Charles L. Sherman at Barnes Medical College, 1896-1901. The collection includes a scholarship certificate, lecture schedule pamphlet, course cards and matriculation tickets, and a leather wallet that originally held the academic cards.