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Hildreth discusses the dispute between the Washington University School of Medicine and Barnes Hospital in the early 1960s, and the roles of Edgar M. Queeny (chairman of the Trustees of Barnes Hospital), Edward W. Dempsey (dean of the medical school), consultants Joseph Hinsey and John H. Knowles, and Washington University chancellor George Pake. Hildreth also talks about some of the faculty of the medical school while he was a student in the mid-1920s, such as Evarts A. Graham and Joseph Erlanger.

Gilson discusses the research and activities of the Department of Physiology at the Washington University School of Medicine in the 1920s and 1930s and several of his colleagues, such as Joseph Erlanger, Herbert Gasser, and George Bishop. He also talks of the axonologists, a discussion group first formed in 1930 at an American Physiological Society meeting.