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This collection consists of 724 photographs, drawings, diagrams, posters, newspaper clippings, and sheet music, and other ephemera related to the 21st General Hospital. The photographs primarily depict staff and patients of the 21st General Hospital from when it was stationed overseas 1942-1945, as well as views of hospital buildings and grounds. Drawings and diagrams include plans for wiring and plumbing, architectural and ground plans, and some schematic drawings of hospital equipment. Other ephemera in the collection include hand-drawn posters advertising Officers' Club dances, newspaper clippings from the St. Louis Post-Dispatch Pictures Section depicting operations at General Hospital 21, and cartoon watercolors depicting soldiers and Red Cross workers.

Correspondence of James Barrett Brown, Lieutenant Colonel in the U.S. Army Medical Corps, while chief of plastic surgery at the Valley Forge General Hospital, Phoenixville, Pennsylvania, 1943-1945. Also contains files of photographs of patients illustrating treatments. The collection includes 20 reprints, dating from 1931 to 1942.

This collection consists of 137 photographs and drawings documenting the years Benjamin H. Charles spent serving as a major for the 21st General Hospital during World War II. The collection includes photographs of Charles, fellow hospital staff and other military personnel, and German prisoners of war (POWs) at various locations in France, Germany, Italy, Morocco, and Algeria. The collection also includes watercolors depicting Charles and various scenes from Bou Hanifia, Algeria by German POW Walter Köhnlein, as well as several promissory notes and a Taittinger champagne label.

19 reprints of scientific journal articles, mostly dealing with dermatopathology. Also biographical sketch of Cooper written by Morris D. Marcus, MD, and one photograph of Cooper in a laboratory with other people including Major G. Seelig.

The Sherwood Moore papers include correspondence, notes, reports, manuscripts, and reprints of articles. They document Dr. Moore’s interests in radiology, cholescystography, hospital administration, and his involvement in the work of Barnes Hospital, Mallinckrodt Institute of Radiology, St. Louis Maternity Hospital, the School of Medicine administration, and the Department of Radiology.

This collection consists of 19 photographs related to the career of Jacques J. Bronfenbrenner. Depicted subjects include signed portraits of Bronfenbrenner's colleagues Hiromu Tsuchiya and Kenneth L. Burdon, photographs of members of the Institut Pasteur in Paris, group portraits of the Washington University School of Medicine Department of Bacteriology and Immunology, and Bronfenbrenner at the Rockefeller Institute with Hideyo Noguchi.

This collection consists of 85 photographs and drawings documenting a range of subjects in the personal and professional life of Dr. Vilray P. Blair (1871-1955). The collection includes photographs of Blair, his family and colleauges, and his residence in Florissant, Missouri. Other depicted subjects from Blair's professional career include his operating room at Barnes Hospital specially decorated by artist Gisella Loeffler (1900-1977), his plaster cast shop, and a selection of his plastic surgery patients. Several of the patient photographs appear in Dr. Blair's published papers, including: "The Surgical Restoration of the Lining of the Mouth" (1923), "The Full Thickness Skin Graft" (1924), and "The Problem of Bringing Forward the Retracted Upper Lip and Nose" (1926).

This collection consists of 43 group portraits of Barnes Hospital Medical and Surgical staff from 1919-1952.

This collection consists of 666 photographs depicting case study patients, x-rays, kymograms, cholecystograms, autopsy specimens, gallbladder cholangiograms, and various figures used in research publications by Wendell G. Scott.

This collection consists of 9 portrait photographs depicting Park J. White. The photographs are all copy prints and several of the portraits were published in the Spring 1982 edition of Outlook Magazine as part of an article profiling White titled "A Coming of Age with Pediatrics."